Summary of the research lines
- Structure and function of the integrated CA domain of mitocondrial complex I in plants and diatoms
- Role of mitochondrial complex I during embryoenesis and photorespiration in plants.
- Role of mitocondrial complex I in the life cycle of diatoms.
- Role of cytochromes P450 during gametogenesis and early embryogenesis in plants.
- Ferroptosis in plants: molecular basis, regulation and biotechnological applications
Financial Support
- Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT)
- Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
- Universidad Nacional del Mar del Plata (UNMdP)
Members
Director
Dr. Eduardo Zabaleta
Principal Researcher CONICET - Adjunct Profesor UNMdP
Eduardo leads projects involving mitochondrial complex I during the embryogenesis and photorrespiration in plants. He is especially interested in the role of the CA domain, which represents the initial step of complex I assembly and that is composed by proteins that are similar to gamma type carbonic anhydrases. In addition, Eduardo studies the presence of a homolog CA domain integrated in the complex I of diatoms and its participation during the life cycle, growth (biomass) and photorespiration in diatoms.
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CoDirector
Dra. Gabriela Pagnussat
Independent Researcher CONICET
Gabriela is focused on the study of plant development and regulated cell death. She is particularly interested in gametogenesis, early embryogenesis and in plant ferroptosis. Using genomic, molecular and biochemical tools, the group goal is to dissect the molecular mechanisms underlying these processes.
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Dra. Ayelén Distéfano
Assistant Researcher CONICET
Ayelén is focused on the characterization of the molecular events that lead to ferroptosis in plants, particularly in response to abiotic stresses in the model plant Arabidopsis thaliana.
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Dra. Fernanda Marchetti
Post-doctoral fellow
Fernanda is studying the role of cytochrome P450 proteins in the liverwort Marchantia polymorpha. Using Crispr/Cas9, her goal is to determine if one of these proteins are functional during the development of the gametophyte, as occurs in angiosperms.
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Lic. Nicolas Setzes
CONICET doctoral fellow
Nicolas is interested in the study of mitochondrial cytochromes P450s during plant development and reproduction, specially focusing on those involved in steroid biosynthesis during gametogenesis.
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Lic. Milagros Cascallares
Becaria Doctoral CONICET
Milagros studies the role of CYP77A7, a P450 cytochrome of unknown function, during vegetative and reproductive development of the model plant Arabidopsis thaliana.a
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Lic. Victoria Bauer
Becaria Doctoral CONICET
Victoria studies the molecular bases of ferroptosis cell death in plants.
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Lic. Gabriel López
Becario Doctoral AGENCIA
Gabriel studies the molecular bases of thermotolerance observed in plants after treatment with ferroptosis inhibitors.
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+54 223 4753030 int 18